Research Direction
1. Acoustic Wave Interactions
We investigate how acoustic waves interact with fluid, interfaces, and suspended particles to reveal new physical mechanisms for actuation and sensing. Our work focuses on acoustic radiation forces, resonant oscillations, and wave-induced interface dynamics that produce complex particle trajectories, rotating wave modes, and structured patterns. By integrating experiments, modeling, and high-speed characterization, we uncover how acoustic waves couple with deformable boundaries and biological structures, enabling new forms of precision control, measurement, and wave-field engineering.
2. Acoustic Characterization and Manipulation of Bioparticles
We develop acoustics-based platforms to measure the biophysical properties of bioparticles ranging from microscale cells to sub-millimeter whole organisms. Acoustic radiation forces, resonant modes, and vibration-assisted sensing enable precise manipulation and quantitative measurement of key properties such as morphology and stiffness. Our goal is to create intelligent acoustic systems that uncover biophysical features in cells and particles that traditional biochemical markers cannot detect.
3. Acoustics-Enabled Bioinstrumentation Systems
We aim to design next-generation instrumentation that uses acoustic manipulation, acoustic sensing, and adaptive control to automate biological assays and improve measurement reproducibility. By integrating acoustic and microfluidic devices, resonant sensing, machine learning, and real-time feedback, we aim to build devices that can immobilize, rotate, measure, and sort biological samples, including organoids, cells, and small organisms, without physical contact. These acoustic systems provide powerful capabilities for long-term culture, high-throughput phenotyping, and quantification of non-visual biophysical properties.
