Publications
| 35 | Reconstructing physiological oxygen gradients reveals the role of hypoxia in colon epithelial organization Jiaquan Yu, Chuyi Chen, Felicia H. Rodriguez, Gianfranco L. Yee, Isabella Y. Zeng, Kevin Yang, Elizabeth K. Benitez, Karuna Ganesh, Scott R. Manalis Available at: bioRxiv |
| 34 | Scavenger submerged microfluidics for chemostatic organoid culture with physiologically relevant oxygen profiles J Yu, C Chen, FH Rodriguez, GL Yee, IY Zeng, K Yang, EK Benitez, K Ganesh, SR Manalis Submitted |
| 33 | Inertial sensing of water content in tumor spheroids G Katsikis, JC Yoon, TR Usherwood, S Malinowski, J Yu, C Chen, S Son, JL Sutton, KL Ligon, J Lee, TP Miettinen, SR Manalis Available at: bioRxiv |
| 32 | Acoustic tweezers for advancing precision biology and medicine Shujie Yang, Joseph Rufo, Ying Chen, Chuyi Chen, Bruce W Drinkwater, Luke P Lee, Tony Jun Huang Nature Reviews Methods Primers 5 (1), 49 Available at: https://www.nature.com/articles/s43586-025-00415-w |
| 31 | Acoustofluidic spin control for 3D particle manipulation in droplets Chuyi Chen, Yuyang Gu, Joseph Rufo, Jinxin Zhang, Kaichun Yang, Ying Chen, Luke P Lee, Tony Jun Huang Science Advances 11 (20), eadx0269 Available at: https://www.science.org/doi/full/10.1126/sciadv.adx0269 |
| 30 | Joint subarray acoustic tweezers enable controllable cell translation, rotation, and deformation Liang Shen, Zhenhua Tian, Kaichun Yang, Joseph Rich, Jianping Xia, Neil Upreti, Jinxin Zhang, Chuyi Chen, Nanjing Hao, Zhichao Pei, Tony Jun Huang Nature Communications 15 (1), 9059 Available at: https://www.nature.com/articles/s41467-024-52686-8 |
| 29 | Acoustofluidic virus isolation via bessel beam excitation separation technology Jianping Xia, Zeyu Wang, Ryan Becker, Feng Li, Fang Wei, Shujie Yang, Joseph Rich, Ke Li, Joseph Rufo, Jiao Qian, Kaichun Yang, Chuyi Chen, Yuyang Gu, Ruoyu Zhong, Patty J Lee, David TW Wong, Luke P Lee, Tony Jun Huang ACS nano 18 (33), 22596-22607 Available at: https://pubs.acs.org/doi/abs/10.1021/acsnano.4c09692 |
| 28 | Acousto-dielectric tweezers enable independent manipulation of multiple particles Liang Shen, Zhenhua Tian, Kaichun Yang, Joseph Rich, Jinxin Zhang, Jianping Xia, Wesley Collyer, Brandon Lu, Nanjing Hao, Zhichao Pei, Chuyi Chen, Tony Jun Huang Science advances 10 (32), 2024 Available at: https://www.science.org/doi/abs/10.1126/sciadv.ado8992 |
| 27 | High-yield and rapid isolation of extracellular vesicles by flocculation via orbital acoustic trapping: FLOAT J Rufo, P Zhang, Z Wang, Y Gu, K Yang, J Rich, C Chen, R Zhong, K Jin, Y He, J Xia, K Li, J Wu, Y Ouyang… Microsystems & Nanoengineering 10 (1), 23, 2024 Available at: https://www.nature.com/articles/s41378-023-00648-3.pdf |
| 26 | A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER) J Zhang, C Chen, R Becker, J Rufo, S Yang, J Mai, P Zhang, Y Gu, Z Wang, Z Ma, J Xia, N Hao, Z Tian… Science Advances 8 (47), eade0640, 2022 Available at: https://www.science.org/doi/full/10.1126/sciadv.ade0640 |
| 25 | Harmonic acoustics for dynamic and selective particle manipulation S Yang, Z Tian, Z Wang, J Rufo, P Li, J Mai, J Xia, H Bachman, PH Huang, M Wu, C Chen, LP Lee, TJ Huang Nature materials 21 (5), 540-546, 2022 Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC9200603/ |
| 24 | Acoustofluidics for simultaneous nanoparticle-based drug loading and exosome encapsulation Z Wang, J Rich, N Hao, Y Gu, C Chen, S Yang, P Zhang, TJ Huang Microsystems & Nanoengineering 8 (1), 45, 2022 Available at: https://www.nature.com/articles/s41378-022-00374-2 |
| 23 | Acoustoelectronic nanotweezers enable dynamic and large-scale control of nanomaterials P Zhang, J Rufo, C Chen, J Xia, Z Tian, L Zhang, N Hao, Z Zhong, Y Gu, K Chakrabarty, TJ Huang Nature communications 12 (1), 3844, 2021 Available at: https://www.nature.com/articles/s41467-021-24101-z |
| 22 | Acoustofluidic rotational tweezing enables high-speed contactless morphological phenotyping of zebrafish larvae C Chen, Y Gu, J Philippe, P Zhang, H Bachman, J Zhang, J Mai, J Rufo, JF Rawls, EE Davis, N Katsanis… Nature communications 12 (1), 1118, 2021 Available at: https://www.nature.com/articles/s41467-021-21373-3 |
| 21 | Fabrication of tunable, high-molecular-weight polymeric nanoparticles via ultrafast acoustofluidic micromixing S Zhao, PH Huang, H Zhang, J Rich, H Bachman, J Ye, W Zhang, C Chen, Z Xie, Z Tian, P Kang, H Fu… Lab on a Chip 21 (12), 2453-2463, 2021 Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC8213440/ |
| 20 | Acoustofluidic centrifuge for nanoparticle enrichment and separation Y Gu, C Chen, Z Mao, H Bachman, R Becker, J Rufo, Z Wang, P Zhang, J Mai, S Yang, J Zhang, S Zhao… Science advances 7 (1), eabc0467, 2021 Available at: https://www.science.org/doi/full/10.1126/sciadv.abc0467 |
| 19 | Acoustofluidic holography for micro-to nanoscale particle manipulation Y Gu, C Chen, J Rufo, C Shen, Z Wang, PH Huang, H Fu, P Zhang, SA Cummer, Z Tian, TJ Huang ACS nano 14 (11), 14635-14645, 2020 Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC7688555/ |
| 18 | Acoustic streaming vortices enable contactless, digital control of droplets P Zhang, C Chen, X Su, J Mai, Y Gu, Z Tian, H Zhu, Z Zhong, H Fu, S Yang, K Chakrabarty, TJ Huang Science Advances 6 (24), eaba0606, 2020 Available at: https://www.science.org/doi/pdf/10.1126/sciadv.aba0606 |
| 17 | An acoustofluidic device for efficient mixing over a wide range of flow rates H Bachman, C Chen, J Rufo, S Zhao, S Yang, Z Tian, N Nama, PH Huang, TJ Huang Lab on a Chip 20 (7), 1238-1248, 2020 Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c9lc01171d |
| 16 | Acoustofluidic salivary exosome isolation: a liquid biopsy compatible approach for human papillomavirus–associated oropharyngeal cancer detection Z Wang, F Li, J Rufo, C Chen, S Yang, L Li, J Zhang, J Cheng, Y Kim, M Wu, E Abemayor, M Tu, D Chia… The Journal of Molecular Diagnostics 22 (1), 50-59, 2020 Available at: https://www.sciencedirect.com/science/article/pii/S1525157819303952 |
| 15 | Fluorescence-based sorting of Caenorhabditis elegans via acoustofluidics J Zhang, JH Hartman, C Chen, S Yang, Q Li, Z Tian, PH Huang, L Wang, JN Meyer, TJ Huang Lab on a Chip 20 (10), 1729-1739, 2020 Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/d0lc00051e |
| 14 | A disposable acoustofluidic chip for nano/microparticle separation using unidirectional acoustic transducers S Zhao, M Wu, S Yang, Y Wu, Y Gu, C Chen, J Ye, Z Xie, Z Tian, H Bachman, PH Huang, J Xia, P Zhang… Lab on a Chip 20 (7), 1298-1308, 2020 Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/d0lc00106f |
| 13 | Acoustofluidic synthesis of particulate nanomaterials PH Huang, S Zhao, H Bachman, N Nama, Z Li, C Chen, S Yang, M Wu, SP Zhang, TJ Huang Advanced Science 6 (19), 1900913, 2019 Available at: https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201900913 |
| 12 | Wave number–spiral acoustic tweezers for dynamic and reconfigurable manipulation of particles and cells Z Tian, S Yang, PH Huang, Z Wang, P Zhang, Y Gu, H Bachman, C Chen, M Wu, Y Xie, TJ Huang Science advances 5 (5), eaau6062, 2019 Available at: https://www.science.org/doi/pdf/10.1126/sciadv.aau6062 |
| 11 | Cell lysis via acoustically oscillating sharp edges Z Wang, PH Huang, C Chen, H Bachman, S Zhao, S Yang, TJ Huang Lab on a Chip 19 (24), 4021-4032, 2019 Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c9lc00498j |
| 10 | Plastic-based acoustofluidic devices for high-throughput, biocompatible platelet separation Y Gu, C Chen, Z Wang, PH Huang, H Fu, L Wang, M Wu, Y Chen, T Gao, J Gong, J Kwun, GM Arepally… Lab on a Chip 19 (3), 394-402, 2019 Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c8lc00527c |
| 9 | Separating extracellular vesicles and lipoproteins via acoustofluidics M Wu, C Chen, Z Wang, H Bachman, Y Ouyang, PH Huang, Y Sadovsky, TJ Huang Lab on a Chip 19 (7), 1174-1182, 2019 Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c8lc01134f |
| 8 | Surface acoustic waves enable rotational manipulation of Caenorhabditis elegans J Zhang, S Yang, C Chen, JH Hartman, PH Huang, L Wang, Z Tian, P Zhang, D Faulkenberry, JN Meyer… Lab on a Chip 19 (6), 984-992, 2019 Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c8lc01012a |
| 7 | Contactless, programmable acoustofluidic manipulation of objects on water P Zhang, C Chen, F Guo, J Philippe, Y Gu, Z Tian, H Bachman, L Ren, S Yang, Z Zhong, PH Huang, N Katsanis… Lab on a Chip 19 (20), 3397-3404, 2019 Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c9lc00465c |
| 6 | Circulating tumor cell phenotyping via high‐throughput acoustic separation M Wu, PH Huang, R Zhang, Z Mao, C Chen, G Kemeny, P Li, AV Lee, R Gyanchandani, AJ Armstrong, M Dao… Small 14 (32), 1801131, 2018 Available at: https://onlinelibrary.wiley.com/doi/am-pdf/10.1002/smll.201801131 |
| 5 | Digital acoustofluidics enables contactless and programmable liquid handling SP Zhang, J Lata, C Chen, J Mai, F Guo, Z Tian, L Ren, Z Mao, PH Huang, P Li, S Yang, TJ Huang Nature communications 9 (1), 2928, 2018 Available at: https://www.nature.com/articles/s41467-018-05297-z |
| 4 | Three-dimensional numerical simulation and experimental investigation of boundary-driven streaming in surface acoustic wave microfluidics C Chen, SP Zhang, Z Mao, N Nama, Y Gu, PH Huang, Y Jing, X Guo, F Costanzo, TJ Huang Lab on a Chip 18 (23), 3645-3654, 2018 Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c8lc00589c |
| 3 | Isolation of exosomes from whole blood by integrating acoustics and microfluidics M Wu, Y Ouyang, Z Wang, R Zhang, PH Huang, C Chen, H Li, P Li, D Quinn, M Dao, S Suresh, Y Sadovsky… Proceedings of the National Academy of Sciences 114 (40), 10584-10589, 2017 Available at: https://www.pnas.org/doi/pdf/10.1073/pnas.1709210114 |
| 2 | Harmonic responses and cavitation activity of encapsulated microbubbles coupled with magnetic nanoparticles Y Gu, C Chen, J Tu, X Guo, H Wu, D Zhang Ultrasonics Sonochemistry 29, 309-316, 2016 Available at: https://www.sciencedirect.com/science/article/pii/S1350417715300493 |
| 1 | Microbubble oscillating in a microvessel filled with viscous fluid: A finite element modeling study C Chen, Y Gu, J Tu, X Guo, D Zhang Ultrasonics 66, 54-64, 2016 Available at: Link |