Publications

27High-yield and rapid isolation of extracellular vesicles by flocculation via orbital acoustic trapping: FLOAT
J Rufo, P Zhang, Z Wang, Y Gu, K Yang, J Rich, C Chen, R Zhong, K Jin, Y He, J Xia, K Li, J Wu, Y Ouyang…

Microsystems & Nanoengineering 10 (1), 23, 2024
Available at: https://www.nature.com/articles/s41378-023-00648-3.pdf
26A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER)
J Zhang, C Chen, R Becker, J Rufo, S Yang, J Mai, P Zhang, Y Gu, Z Wang, Z Ma, J Xia, N Hao, Z Tian…

Science Advances 8 (47), eade0640, 2022
Available at: https://www.science.org/doi/full/10.1126/sciadv.ade0640
25
Harmonic acoustics for dynamic and selective particle manipulation
S Yang, Z Tian, Z Wang, J Rufo, P Li, J Mai, J Xia, H Bachman, PH Huang, M Wu, C Chen, LP Lee, TJ Huang

Nature materials 21 (5), 540-546, 2022
Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC9200603/
24Acoustofluidics for simultaneous nanoparticle-based drug loading and exosome encapsulation
Z Wang, J Rich, N Hao, Y Gu, C Chen, S Yang, P Zhang, TJ Huang

Microsystems & Nanoengineering 8 (1), 45, 2022
Available at: https://www.nature.com/articles/s41378-022-00374-2
23Acoustoelectronic nanotweezers enable dynamic and large-scale control of nanomaterials
P Zhang, J Rufo, C Chen, J Xia, Z Tian, L Zhang, N Hao, Z Zhong, Y Gu, K Chakrabarty, TJ Huang

Nature communications 12 (1), 3844, 2021
Available at: https://www.nature.com/articles/s41467-021-24101-z
22Acoustofluidic rotational tweezing enables high-speed contactless morphological phenotyping of zebrafish larvae
C Chen, Y Gu, J Philippe, P Zhang, H Bachman, J Zhang, J Mai, J Rufo, JF Rawls, EE Davis, N Katsanis…

Nature communications 12 (1), 1118, 2021
Available at: https://www.nature.com/articles/s41467-021-21373-3
21Fabrication of tunable, high-molecular-weight polymeric nanoparticles via ultrafast acoustofluidic micromixing
S Zhao, PH Huang, H Zhang, J Rich, H Bachman, J Ye, W Zhang, C Chen, Z Xie, Z Tian, P Kang, H Fu…

Lab on a Chip 21 (12), 2453-2463, 2021
Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC8213440/
20Acoustofluidic centrifuge for nanoparticle enrichment and separation
Y Gu, C Chen, Z Mao, H Bachman, R Becker, J Rufo, Z Wang, P Zhang, J Mai, S Yang, J Zhang, S Zhao…

Science advances 7 (1), eabc0467, 2021
Available at: https://www.science.org/doi/full/10.1126/sciadv.abc0467
19Acoustofluidic holography for micro-to nanoscale particle manipulation
Y Gu, C Chen, J Rufo, C Shen, Z Wang, PH Huang, H Fu, P Zhang, SA Cummer, Z Tian, TJ Huang

ACS nano 14 (11), 14635-14645, 2020
Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC7688555/
18Acoustic streaming vortices enable contactless, digital control of droplets
P Zhang, C Chen, X Su, J Mai, Y Gu, Z Tian, H Zhu, Z Zhong, H Fu, S Yang, K Chakrabarty, TJ Huang

Science Advances 6 (24), eaba0606, 2020
Available at: https://www.science.org/doi/pdf/10.1126/sciadv.aba0606
17An acoustofluidic device for efficient mixing over a wide range of flow rates
H Bachman, C Chen, J Rufo, S Zhao, S Yang, Z Tian, N Nama, PH Huang, TJ Huang

Lab on a Chip 20 (7), 1238-1248, 2020
Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c9lc01171d
16Acoustofluidic salivary exosome isolation: a liquid biopsy compatible approach for human papillomavirus–associated oropharyngeal cancer detection
Z Wang, F Li, J Rufo, C Chen, S Yang, L Li, J Zhang, J Cheng, Y Kim, M Wu, E Abemayor, M Tu, D Chia…

The Journal of Molecular Diagnostics 22 (1), 50-59, 2020
Available at: https://www.sciencedirect.com/science/article/pii/S1525157819303952
15Fluorescence-based sorting of Caenorhabditis elegans via acoustofluidics
J Zhang, JH Hartman, C Chen, S Yang, Q Li, Z Tian, PH Huang, L Wang, JN Meyer, TJ Huang

Lab on a Chip 20 (10), 1729-1739, 2020
Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/d0lc00051e
14A disposable acoustofluidic chip for nano/microparticle separation using unidirectional acoustic transducers
S Zhao, M Wu, S Yang, Y Wu, Y Gu, C Chen, J Ye, Z Xie, Z Tian, H Bachman, PH Huang, J Xia, P Zhang…

Lab on a Chip 20 (7), 1298-1308, 2020
Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/d0lc00106f
13Acoustofluidic synthesis of particulate nanomaterials
PH Huang, S Zhao, H Bachman, N Nama, Z Li, C Chen, S Yang, M Wu, SP Zhang, TJ Huang

Advanced Science 6 (19), 1900913, 2019
Available at: https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201900913
12Wave number–spiral acoustic tweezers for dynamic and reconfigurable manipulation of particles and cells
Z Tian, S Yang, PH Huang, Z Wang, P Zhang, Y Gu, H Bachman, C Chen, M Wu, Y Xie, TJ Huang

Science advances 5 (5), eaau6062, 2019
Available at: https://www.science.org/doi/pdf/10.1126/sciadv.aau6062
11Cell lysis via acoustically oscillating sharp edges
Z Wang, PH Huang, C Chen, H Bachman, S Zhao, S Yang, TJ Huang

Lab on a Chip 19 (24), 4021-4032, 2019
Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c9lc00498j
10Plastic-based acoustofluidic devices for high-throughput, biocompatible platelet separation
Y Gu, C Chen, Z Wang, PH Huang, H Fu, L Wang, M Wu, Y Chen, T Gao, J Gong, J Kwun, GM Arepally…

Lab on a Chip 19 (3), 394-402, 2019
Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c8lc00527c
9Separating extracellular vesicles and lipoproteins via acoustofluidics
M Wu, C Chen, Z Wang, H Bachman, Y Ouyang, PH Huang, Y Sadovsky, TJ Huang

Lab on a Chip 19 (7), 1174-1182, 2019
Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c8lc01134f
8Surface acoustic waves enable rotational manipulation of Caenorhabditis elegans
J Zhang, S Yang, C Chen, JH Hartman, PH Huang, L Wang, Z Tian, P Zhang, D Faulkenberry, JN Meyer…

Lab on a Chip 19 (6), 984-992, 2019
Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c8lc01012a
7Contactless, programmable acoustofluidic manipulation of objects on water
P Zhang, C Chen, F Guo, J Philippe, Y Gu, Z Tian, H Bachman, L Ren, S Yang, Z Zhong, PH Huang, N Katsanis…

Lab on a Chip 19 (20), 3397-3404, 2019
Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c9lc00465c
6Circulating tumor cell phenotyping via high‐throughput acoustic separation
M Wu, PH Huang, R Zhang, Z Mao, C Chen, G Kemeny, P Li, AV Lee, R Gyanchandani, AJ Armstrong, M Dao…

Small 14 (32), 1801131, 2018
Available at: https://onlinelibrary.wiley.com/doi/am-pdf/10.1002/smll.201801131
5Digital acoustofluidics enables contactless and programmable liquid handling
SP Zhang, J Lata, C Chen, J Mai, F Guo, Z Tian, L Ren, Z Mao, PH Huang, P Li, S Yang, TJ Huang

Nature communications 9 (1), 2928, 2018
Available at: https://www.nature.com/articles/s41467-018-05297-z
4Three-dimensional numerical simulation and experimental investigation of boundary-driven streaming in surface acoustic wave microfluidics
C Chen, SP Zhang, Z Mao, N Nama, Y Gu, PH Huang, Y Jing, X Guo, F Costanzo, TJ Huang

Lab on a Chip 18 (23), 3645-3654, 2018
Available at: https://pubs.rsc.org/en/content/getauthorversionpdf/c8lc00589c
3Isolation of exosomes from whole blood by integrating acoustics and microfluidics
M Wu, Y Ouyang, Z Wang, R Zhang, PH Huang, C Chen, H Li, P Li, D Quinn, M Dao, S Suresh, Y Sadovsky…
Proceedings of the National Academy of Sciences 114 (40), 10584-10589, 2017
Available at: https://www.pnas.org/doi/pdf/10.1073/pnas.1709210114
2Harmonic responses and cavitation activity of encapsulated microbubbles coupled with magnetic nanoparticles
Y Gu, C Chen, J Tu, X Guo, H Wu, D Zhang

Ultrasonics Sonochemistry 29, 309-316, 2016
Available at: https://www.sciencedirect.com/science/article/pii/S1350417715300493
1Microbubble oscillating in a microvessel filled with viscous fluid: A finite element modeling study
C Chen, Y Gu, J Tu, X Guo, D Zhang
Ultrasonics 66, 54-64, 2016
Available at: Link